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…Background Lynch syndrome (LS) is defined by having a pathogenic constitutional variant a…

…Introduction Colonoscopy surveillance in Lynch syndrome (LS) has historically shown substantial heterogeneity in qualit…

…tumours, as deficient MMR is important for (1) the detection of Lynch Syndrome, caused by inherited variants affecting the DNA MMR genes MLH1,…

…ommended and implemented as a standard of care in patients with endometrial cancer (EC); however, few such studies have been published on Canadian…

…Background Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (…

…mic instability.Results The first case describes a patient with Lynch Syndrome developing a low-grade TNBC of the left breast with adenoid cys…

…h LS with a known germline MLH1 mutation who was diagnosed with Cushing’s syndrome. An ectopic adrenocorticotropic hormone (ACTH) producing carcin…

…or early diagnosis and prevention of colorectal cancer (CRC) in Lynch syndrome (LS). Since July 2023 in England, colonoscopic surveillance has…

…ch syndrome. Their child, initially healthy, was diagnosed with acute bilineal leukaemia and later found to have CMMRD. His diagnosis highlighted gaps i…

…ne (5-ASA, 5-aminosalicylic acid), used safely in patients with ulcerative colitis, may reduce CRC risk in LS by decreasing microsatellite instabi…

…at lowering cancer incidence by targeting premalignant lesions. Lynch syndrome (LS), one of the most prevalent hereditary cancer syndromes, is…

…Background Lynch syndrome (LS) is among the most common hereditary cancer predisposition …