ICANSviral encephalitisUniversity College London HospitalsCAR T-cell therapyUCLHhaemato-oncology service
…emato-oncology service between May 2019 - December 2022.Results ICANS occurred in 48% patients treated(100/208), clinical seizure act…
7articles mentioning diseases
30disease mentions
1distinct diseases extracted
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ICANS
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Articles mentioning ICANS
7 articles · page 1 of 1multiple myelomaDLBCLacute lymphoblastic leukaemiadiffuse large B-cell lymphomaICANSMMALLcytokine release syndromeimmune effector cell-associated neurotoxicity syndrome (ICANS)
…= 53, 76%), acute lymphoblastic leukaemia (ALL, n = 6, 9%), and multiple myeloma (MM, n = 6, 9%). CAR-T products: axicabtagene ciloleucel (n = 3…
haematological malignanciesautoimmune neurological disordersICANSimmune effector cell-associated neurotoxicity syndrome (ICANS)ICANS-relatedChimeric antigen receptor T-cell (CAR-T) therapyThe Alfred Hospital
…cell (CAR-T) therapy has transformed the treatment landscape of haematological malignancies and is being trialled for autoimmune neurological disorders. Ho…
ICANS
…the anti-tumor efficacy and all reported toxicities – including ICANS - associated with CAR19 clinical therapy. In our model, intrave…
Burkitt lymphomaB-cell acute lymphoblastic leukemiaB-ALLCAYAICANSsiltuximab
…ort. 30 CAYA were treated at the RP2D; 28 with B-ALL and 2 with Burkitt lymphoma. Across patients with B-ALL, 20 (71.4%) patients developed cyto…
RRMMICANSmultiple myelomatalquetamabtocilizumabrasburicasadexamethasone
…myeloma cells, used in relapsed or refractory multiple myeloma (RRMM). While pivotal trials have shown promising results, real-world…
haematological malignanciesImmune Effector Cell-Associated Neurotoxicity Syndrome (ICANS)ICANSChimeric Antigen Receptor T-cell (CAR-T) therapyCAR-T therapy
…ptor T-cell (CAR-T) therapy has revolutionised the treatment of haematological malignancies. Despite its efficacy, CAR-T therapy is associated with a high …