Browse diseases

… in tens to hundreds of patients (figure 1b). For patients with melanoma, Morpheus predicted that combinatorial perturbation to the CXCL…

…Background Colorectal cancer (CRC) is the third leading cause of death in the US and is incr…

…ified tissue-specific intratumor microbes, including those from colorectal metastases (33), bone metastases (22), sarcoma metastases (8), kidney meta…

…f b-catenin/BCL9 with ST316 as a novel therapeutic approach for CRC.Ethics Approval All aspects of animal care were in accordance w…

… with KRAS gene (p=8.0E-04; colorectal cancer), SPEN (p=3.E-04; breast cancer), ARID1A (p=2.2E-04; kidney cancer), and TRIM51 (p=2.3E-04; lun…

…MA) comprising specimens of multiple human cancer types, namely prostate cancer, lung cancer, breast cancer, colorectal cancer, melanoma, and l…

…enchymal transition (EMT), TNF-α and TGF-β, in both independent CRC cohorts. Regional bulk RNA expression revealed that cell cycle …

…ll lung cancer (NSCLC, n=30), colorectal cancer (CRC, n=33) and urothelial cancer (UC, n=30) resection samples. We present a comparative analysis…

…, the 75-year-old male Vietnamese patient with liver-metastatic CRC harboring KRAS, PIK3CA, PTEN, and TP53 mutations exhibited diff…

…dance (p < 0.001). MAIT cells were lower in non-small cell lung cancer patients with high PD-L1 status by IHC (TPS > 50%; p < 0.001). …

…erformed clinical validations in triple-negative breast cancer, non-small cell lung cancer, colorectal cancer, and other tumor types. In this study, we ev…

…uency, occurring in 28% and 12% of pancreatic cancer (PDAC) and colorectal cancer (CRC), respectively. KRAS G12D-containing peptides are presente…