Browse diseases

…ed in subcutaneous murine colon carcinoma (CT26, n=5/group) and pancreatic adenocarcinoma (KPC, n=10-11/group) models. Plasma interferon gamma levels (IF…

… states in CT26 tumors and shifts in CD8 + T cell phenotypes in MC38 tumors. These findings support the immunostimulatory potential …

…tat, in different ICB-refractory murine tumor models, including CT26 (colorectal) and MOC-1 (HPV16 neg head and neck).Methods Mice r…

…rious mouse syngeneic tumor models, including CT26, B16F10, and Nooc1. Tumor and tumor draining lymph nodes were collected and analyz…

…ficantly inhibited tumor growth and improved survival in EMT-6, CT26, and 4T1 models, outperforming either monotherapy or the STING …

…only underlie resistance to immune checkpoint blockade (ICB) in solid malignancies. Novel combination therapies may overcome these barriers, provi…