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…R2 and CCR5 antagonists have demonstrated antitumor activity in pancreatic ductal adenocarcinoma (PDAC) and colorectal cancer (CRC), respectively. This phase 1b…

…Background The overall rates of colorectal cancer (CRC) in the US population have been declining steadily over th…

…), metabolic-associated steatohepatitis (MASH), and the risk of colorectal cancer (CRC) and benign colorectal neoplasms (BCN), and to explore whe…

…Colorectal cancer (CRC) is one of the most common malignant cancers and its incid…

…enchymal transition (EMT), TNF-α and TGF-β, in both independent CRC cohorts. Regional bulk RNA expression revealed that cell cycle …

…n to demonstrate causality.Results Western diet exacerbated the CRC phenotype in APC 1311/+ pigs. This was accompanied by increased…

…Pan-cancer expression datasets (VLCFA elongation complex genes).Colorectal cancer (CRC) tissues/cells (focus on TECR upregulation).MethodsSystema…

…Background Colorectal cancer (CRC) is a major cause of cancer mortality worldwide, with meta…

…nted case activity will be necessary in future population-level CRC surveillance research.…

…ttern. The pattern and several metabolites were associated with CRC risk, providing biological insights into potential pathways und…

…allele. The top mutated genes were TP53 (71%) and APC (63%) for CRC, TP53 (76%) and CDKN2A (28%) for PDAC, GNAS (34%) and TP53 (34%…

…ables and CRC risk were estimated using Cox regressions.Results CRC risk did not differ between nurses who ever or never worked nig…