Browse diseases

…Objective There are 44 000 new cases of colorectal cancer (CRC) and 16 000 deaths in the UK annually. Most CRCs are diagn…

…Stromal cell sialylation modulates innate immune suppression in CRC via the sialic acid/Siglec axis. Targeting stromal sialylation …

… higher in the HR-HR group (SIR 2.84, 1.30 to 5.39). After SC2, CRC incidence in the HR-HR group was no longer higher than in the g…

…Colorectal cancer (CRC) remains a leading cause of cancer-related mortality world…

…m peripheral blood mononuclear cells from healthy donors. Human CRC cell lines (BRAFV600E HT29, KRASG12V SW480) and KRAS/APC-mutant…

…Background Depression frequently accompanies colorectal cancer (CRC) and worsens quality of life and outcomes, yet pathways tr…

…ethods We retrospectively reviewed 190 patients with left-sided CRC who underwent PALN dissection at a high-volume center between M…

…nclusions Systemic myeloid remodeling is initiated early during colorectal tumorigenesis and is characterized by progressive expansion of HIF-1 α-positi…

…1.27×10−14), and high AGRN expression was associated with worse CRC survival (hazard ratio=1.25, 95% confidence interval=1.01-1.56,…

…blockade (ICB), has shown clinical promise, but its efficacy in colorectal cancer (CRC) remains limited due to a complex immunosuppressive tumor …

…Background Colorectal cancer (CRC), the third most prevalent malignancy globally, faces ther…

…Introduction Perioperative anaemia in colorectal cancer(CRC) can result in increased complications; longer hospital sta…