…. A maximum tolerated dose was not reached. Two patients (9.5%; uterine sarcoma, porocarcinoma) who received one cycle of S095029 monotherapy f…
Advanced solid tumors
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Articles mentioning Advanced solid tumors
25 articles · page 2 of 3… concluding in a phase I clinical study involving patients with advanced solid tumors ( NCT05229601).…
…lity, pharmacokinetics, and antitumor activity in patients with advanced solid tumors in a Phase 1 study.Methods The study comprised Part 1 ASP9801 m…
…cacy of ILKN421H with or without pembrolizumab in patients with advanced solid tumors. The design includes two portions of the study: Parts A, ILKN42…
…anion diagnostic for pembrolizumab in advanced solid tumors. In MSS mCRC, TMB from tumor tissue (tTMB) provided no predictive utility to…
…bitors (ICIs) remains an urgent unmet need in the management of advanced solid tumors. ICI retreatment has demonstrated minimal clinical benefit. Acc…
…mberelimab (anti-PD1) and mFOLFOX chemotherapy in patients with advanced solid tumors.Methods Here we present peripheral PD data from AB598 monothera…
…ing endothelial, fibroblasts, and immune cells across different solid tumors. No changes in total CD39 protein expression levels were observ…
…Background Advanced solid tumors remain a significant clinical challenge due to their heterogene…
…of 0/1, and histologically/cytologically confirmed diagnosis of la/m solid tumors ineligible for surgical/medical treatment with curative intent,…
…41 per cohort) with recurrent or metastatic non-small cell lung cancer (NSCLC), melanoma, endometrial cancers, or head and neck squamo…
…ays, including IFN-γ signaling and antigen presentation. In the mCRPC patient subset, specific PBMC transcriptomic profiling revealed…