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… echocardiography, standard of care biomarkers, QoL metrics and 6-minute walk test (6MWT) were assessed prior to mavacamten therapy and again foll…

…th Scale, the Pediatric Balance Scale, the Timed Up and Go, the 6-minute walk test, the 10-metre walk test and the Pediatric Quality of Life Inven…

…ax, mL/kg/min) measured by CPET. Secondary outcomes include the 6-Minute Walk Test, 30-Second Sit-to-Stand, Short Physical Performance Battery, fo…

…eline values and 12-month change in the 6-Minute Walk Distance (6MWD) and the physical scale of the Minnesota Living with Heart Fail…

…rating procedures, a TLCO result with a Z-score < -1.645, and a 6-minute walk test with oxygen saturation nadir <95% measured by pulse oximetry. P…

…luded 6MWD, spirometry, St. George’s Respiratory Questionnaire (SGRQ), gender, race and CT measures of emphysema, gas trapping and a…

…by the local multidisciplinary Heart Team 2. Patients underwent 6-minute walk test (6MWT) and CMR within 1-month prior to MVI, and 6-months after.…

…diography (E/A ratio, LVEF), modified Rodnan skin score (mRSS), 6-minute walk test (6MWT), nailfold videocapillaroscopy (NVC), and serological mar…

…lth (Scleroderma Health Assessment Questionnaire (SHAQ) and the Hospital Anxiety and Depression Scale (HADS)). For each assessment, the mean and standard deviation a…

…g the Health Assessment Questionnaire (HAQ) and the Scleroderma Health Assessment Questionnaire (SHAQ). Dyspnea severity was assessed using the modified Medica…

…Questionnaire; 3-month changes in dyspnoea severity through the modified Medical Research Council Dyspnoea Scale; and 6-month changes in functional exercise capacity through th…

…m the local communities. MEP will be assessed using an 11-point Numeric Rating Scale during five standardised functional tasks: 30-Second Chair Stan…