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From 28 to 31 October 2026, the Australasian College of Sport and Exercise Physicians (ACSEP) will host its Annual Scientific Conference in Brisbane in conjunction with Sports Medicine Australia (SMA). At a time when healthcare systems, sporting environments and the wider world are navigating profound change, this BJSM ACSEP edition explores a central theme—that of uncertainty. This feels more relevant than ever during these turbulent times.