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Background Children and young people with long term heath conditions are more likely to experience psychosocial and mental health challenges. Tree of Life (ToL) groups (Ncube, 2006) that were designed to support people with medical conditions, and to be delivered by non-mental health professionals, have been delivered in paediatric settings with positive outcomes. In the context of long waiting times for psychology, this study aimed to test if positive outcomes could be maintained if: Participants were children already referred to psychology rather than self-selected; group members had different medical conditions instead of the same; groups were led by pre-qualification psychology staff to spare qualified clinicians for more complex interventions. Finally, parallel ToL groups for parents were also piloted in response to feedback from previously run groups.Methods Qualitative and quantitative feedback was obtained from 48 child (7-18yrs) and 12 parent attendees. A focus group was also conducted with the pre-qualification group facilitators to determine their experience. Data on adverse events was also recorded.Results Patient and parent feedback were very positive and themes reflected those from previous studies. However, fewer than 50% of invitees attended the groups with older adolescents much less likely to attend suggesting that the group did not appeal to everyone. Feedback from pre-qualification staff was also positive but emphasised the value of training and support provided by qualified staff.Conclusion There was support for continuing the groups in the current format, led by pre-qualification staff. However, further consideration is required about the high level of non-attendance.Acknowledgements for Funding or Support This research project has been completed with the support of members of the Psychological & Mental Health Services at Great Ormond Street Children’s Hospital.