Uncommon manifestation of invasive group A Streptococcus infection: Lemierre syndrome with multiple pulmonary complications

Lemierre syndrome is an uncommon disease most often associated with Fusobacterium necrophorum infections. We present a case of Lemierre syndrome associated with Streptococcus pyogenes infection with pulmonary abscess, septic emboli and empyema requiring chest tube drainage and intrapleural fibrinolytic therapy. Our case highlights S. pyogenes as an uncommon cause of Lemierre syndrome as well as the challenges in treating complications of such infections.