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Chinese expert consensus on the diagnosis and treatment of female primary pelvic retroperitoneal tumours (2025 edition)

gocm · 2025-12-12 · canonical JSON source

7 visible annotations · policy: published · automated confidence ≥ 75.00%

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Female primary pelvic retroperitoneal tumours (PPRTs) refer to a heterogeneous group of tumours originating from the retroperitoneal space of the female pelvis, located predominantly or entirely within the true pelvis. This group excludes metastatic tumours, bone-derived tumours, extragastrointestinal stromal tumours, broad ligament myomas, endometriosis, tumours originating from the lymphoreticular system and tumours originating from pelvic visceral organs (such as those of the female reproductive tract, intestines and urinary system). PPRTs, also known as pelvic extraperitoneal tumours, have an incidence rate of less than 0.01%. The upper boundary of the pelvic retroperitoneal space is defined by a line consisting of the superior border of the symphysis pubis, the pubic tubercle and the superior border of the sacral promontory, whereas the inferior boundary extends to the pelvic diaphragm or below. Most female PPRTs are diagnosed during reproductive age, with approximately 80% of the tumours being benign.1 The management of PPRTs poses challenges for general clinicians due to their limited clinical experience, which leads to a high rate of missed cases and misdiagnoses. Compared with abdominal retroperitoneal tumours, the anatomical structure of PPRTs is deeper and more complex, resulting in greater surgical difficulty. Currently, there is a lack of relevant guidelines or consensus regarding diagnosis and treatment.2 Therefore, the Chinese Society of Gynaecologic Oncology, Chinese Medical Association and the Gynaecologic Oncology Group of the Branch of Obstetricians and Gynaecologists, Chinese Medical Doctor Association formulated this consensus after extensive discussions among experts in gynaecologic oncology, pathology and colorectal surgery, along with a review of domestic and international literature, to improve the diagnosis and treatment of female PPRTs. Importantly, this consensus is based primarily on the consistency of expert opinions, as high-quality research evidence is currently lacking.