BetaEntity Annotation Prototype
← Back to diseases

Annotated abstract

C71 Controlled-deployment stent in stroke related to intracranial stenosis: optimising stenosis treatment and allowing distal circulation assessment before final detachment

neurintsurg · 2025-09-02 · canonical JSON source

4 visible annotations · policy: published · automated confidence ≥ 75.00%

Document resource

Introduction In acute ischaemic stroke, unstable intracranial stenoses uncovered after thrombectomy may rapidly reocclude, requiring immediate rescue therapy. No stroke-specific self-expanding stent with controlled deployment is currently available; we present a case illustrating the usefulness of this feature, using Solitaire AB stent off-label.Abstract C71 Figure 1Case Description A late-middle-aged diabetic woman presented at night with right distal M1 occlusion (NIHSS 5–6), significant perfusion mismatch, hypertension. IV thrombolysis was administered. Under GA, combined first-pass thrombectomy achieved eTICI 2c but revealed an unstable focal stenosis, with early reocclusion. Initial centred deployment of a Solitaire AB reopened the artery with moderate calibre gain; aware of Solitaire AB behaviour, the stent was resheathed and redeployed more proximally, achieving further enlargement and final TICI 3. Mid-to-distal coverage may enhance radial support by minimizing the influence of the flared proximal end, as suggested by this technical adjustment. Intravenous tirofiban bolus and infusion were followed the next day by dual antiplatelet loading, after confirming patency and no haemorrhage on CTA. Day 1 NIHSS score: 1–2.Abstract C71 Figure 2Conclusions Controlled-deployment allows real-time evaluation of stent effect on vessel calibre, avoiding unnecessary pre-stent angioplasty, and assessing distal circulation to confirm good TICI before detachment. Aggressive antiplatelet therapy – even after IV thrombolysis if judged appropriate – toghether with high-dose statins and the likely pre-existing compensated stenosis, can support functional recovery and long-term patency even if mild-to-moderate residual narrowing is present, often avoiding also post-stenting angioplasty. Although off-label Solitaire AB is effective, a stroke-specific self-expanding controlled-deployment stent with optimised design would represent a desirable advance.Abstract C71 Figure 3Conflict of Interest No