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The development of a UK Health Data Research Service (HDRS), backed by a £600m investment from the government and Wellcome, could be pivotal to harnessing health data for public benefit.1 The aim is to create a single, secure gateway to health and care data to enable research while maintaining data protection and public trust.2 Achieving this would fuel discovery science, clinical trials, artificial intelligence (AI) innovation, and economic growth. For it to be successful, however, the UK must convert its fragmented health data legacy into a coherent and efficient system.3