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Background Cough hypersensitivity is associated with poor quality of life and high healthcare use. Cough can co-present with dysphonia, inducible laryngeal obstruction (ILO) and dysphagia. Speech and Language Therapists (SLTs) support assessment and management of these disorders.This study reports on data from a specialist upper airway SLT led- laryngoscopy clinic, with access to on-call respiratory physicians and virtual otolaryngology image reviews.Method A retrospective data review was conducted of 139 patients with suspected cough hypersensitivity, who attended the SLT-led laryngoscopy clinic between December 2022 and December 2024. Lidocaine was used for 2 patients. Provocation trials were informed by patient-reported triggers: vocal tasks (n=109, 78.42%), external irritants e.g. aerosol spray (n=79, 56.83%), oral trials including diet and fluids (n=32, 23.02%), and exertion (n=15, 10.79%). Data was collected using electronic health records. Abnormalities were reviewed by an Otolaryngologist.Results No medical emergencies occurred.Diagnoses included cough hypersensitivity (n=114, 82.01%), laryngeal muscle imbalance (n=84, 60.43%), viscous secretions (n=68, 48.92%), laryngeal inflammation (n=19, 13.67%), structural impairment e.g. polyps (n=17, 12.23%), neuromuscular impairment e.g. vocal cord paresis (n=7, 5.04%) and ILO (n=22, 15.82%).Exercise trials included: a) Breath control: Sniff and cheek puff (n=139, 55.40%), Sniff and blow (n=78, 56.12%), Tongue protrusion (n=29, 20.86%), Straw breathing (n=14, 10.07%), Pursed lips breathing (n=10, 7.19%) and others (n=9, 6.47%).b) Muscle tension release: Tongue protrusion (n=72, 51.80%), Yawn (n=91, 65.47%), Inside smile (n=1, 0.72%), other (n=2, 1.44%).c) Voice quality: Humming (n=23, 16.55%) Siren (n=3, 2.16%); Whimper (n=6, 4.32%); Sob (n=6, 4.32%); and others (n=15, 10.79%).98 (70.50%) found breathing exercises to be the most effective, specifically sniff and puff (45/98, 45.92%) and sniff and blow (49/98, 50%).Biofeedback was provided to 135 (97%) patients to support understanding of diagnosis and therapy.Abstract P110 Figure 1Conclusion SLT-led laryngoscopy clinics are safe and do not require medical supervision. They enable co-morbidities to be identified, bespoke management programmes to be developed, and biofeedback to be provided. Further research is needed to look at the longer-term outcomes of these clinics, and patient satisfaction.