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Hospital length of stay (LOS) is an important endpoint in healthcare quality research as it is a composite measure of patient recovery, associated with complications (and readmissions), and a significant driver of healthcare expenditures. 1 Currently, value-based controversy surrounds the use of liposomal bupivacaine (Exparel) for both infiltration and peripheral nerve block, as its substantially higher cost has not consistently translated into improved clinical outcomes.2 3 In thoracic surgery, liposomal bupivacaine is used for intercostal nerve blocks placed by surgeons to facilitate postoperative analgesia.4 As improved analgesia can hasten mobilization and discharge readiness, we assessed whether formulary removal of liposomal bupivacaine impacted hospital LOS following thoracoscopic pulmonary wedge resection.