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Beyond conventional dosing: tailoring antimicrobial regimens for cachexia

ejhpharm · 2025-08-21 · canonical JSON source

4 visible annotations · policy: published · automated confidence ≥ 75.00%

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Cachexia is defined as a loss of more than 5% of body weight or a body mass index (BMI) of less than 20 kg/m² due to chronic disease.1 It involves decreased muscle strength, fatigue, anorexia, reduced fat-free mass and abnormal biomarkers like anaemia and hypoalbuminaemia.2 The exact mechanism is unclear, but it leads to significant changes in fat, carbohydrate and protein metabolism.