Discriminant potential of NT-proBNP for aberrant hyperthermia and inflammatory responses with exercise in the heat

In severe exertional heat illness (EHI), inflammation and endotoxaemia may contribute to debility and death.1 The lack of predictive and diagnostic tools reflects a multifactorial aetiology and complex pathophysiology. This challenge is felt acutely in military organisations responsible for service person (SP) exposure to occupational heat stress.2