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The human cost of overdiagnosis is emotional distress and fear

bmj · 2026-05-18 · canonical JSON source

4 visible annotations · policy: published · automated confidence ≥ 75.00%

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Davies provides a salutary reminder of the harm that can be caused by the diagnoses we make.1 Most melanoma in situ is biologically indolent and will never progress, and the dramatic rise in incidence is largely a marker of diagnostic scrutiny. The absence of a corresponding fall in invasive melanomas is the hallmark of overdiagnosis.2 I hope she will take consolation from the fact that a diagnosis of melanoma in situ is associated with an overall reduced risk of death from any cause over the 15 years after diagnosis, which greatly exceeds any (exceedingly small) risk of death from melanoma.3