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P17 Implementing standardised TERM parenteral nutrition in a level 3 neonatal unit

bmjpo · 2026-04-09 · canonical JSON source

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Aim Bespoke PN prescribing remains common for term neonates despite increasing emphasis on standardisation. The London Neonatal Nutrition Group (LNNG) has proposed a standardised TERM PN formulation for infants ≥37 weeks corrected gestational age who are ineligible for SCAMP (Standardised, Concentrated with Added Macronutrients PN). 1 Methods A four-week pilot was undertaken in a 46-bed level 3 neonatal intensive care unit. During the study period, eight term neonates were eligible for PN, of whom four met inclusion criteria and were commenced on the LNNG-endorsed TERM aqueous PN formulation. 2 The formulation provides lower nitrogen (0.38 g/kg/day at 100 mL/kg/day) and higher glucose (12.5 g/100 mL), consistent with ESPGHAN guidance.3 Outcomes assessed included biochemical stability, nutritional growth parameters (weight and head circumference), and clinician-reported workflow impact.Results Four of eight eligible term neonates (50%) were commenced on the standardised TERM PN formulation. All four infants maintained biochemical parameters within acceptable ranges, with no electrolyte imbalance, metabolic derangement, or adverse clinical events. Growth in weight and head circumference followed expected centile trajectories throughout PN exposure. No safety incidents or Datix reports were recorded, and no infant required reversion to bespoke PN. Clinician feedback indicated improved prescribing consistency and reduced variability. Consultant-reported time savings were approximately 5–10 minutes per PN episode, equating to around two hours of clinician time saved per week compared with bespoke PN prescribing.Conclusion Implementation of a standardised TERM aqueous PN formulation was safe and effective in this pilot cohort, improving prescribing efficiency, consistency, and workflow without compromising nutritional outcomes. With approximately half of eligible term PN patients suitable for this formulation, routine stocking and wider implementation may substantially reduce bespoke PN use. A follow-up audit is planned to assess sustainability and longer-term outcomes.References Morgan C, Herwitker S, Badhawi I et al. SCAMP: standardised, concentrated, additional macronutrients, parenteral nutrition in very preterm infants—a phase IV randomised controlled exploratory study of macronutrient intake, growth and other aspects of neonatal care. BMC Pediatrics 2011;11:53.London Neonatal Nutrition Group. Proposed standard term parenteral nutrition formulation. London Neonatal Operational Delivery Network;2024.Joosten K, Embleton N, Yan W et al. ESPGHAN/ESPEN/ESPR/CSPEN guidelines on paediatric parenteral nutrition: Energy.Clinical Nutrition 2018;37:2309–2314.