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Introduction Acute upper gastrointestinal bleeding (AUGIB) remains a common presentation accounting for 0.1% of acute medical admissions. Current risk stratification to guide management is weighted on patient factors (eg, Glasgow-Blatchford Score, GBS, or Rockall Score, RS). With an increasingly comorbid population these scores may have less utility. We assess blood-detection capsules (BDC) to triage low-risk, non-variceal, AUGIB referrals.Methods A prospective service evaluation was performed at a district general hospital in East London. All AUGIB referrals received during the evaluation period were screened for suitability. The BDC was administered while participants wore an external receiver. If positive, participants underwent inpatient gastroscopy; if negative, they were managed as outpatients. Subsequent results, including complications and mortality, were recorded.Results 21 referrals were screened during the evaluation period. 11 were excluded with the most common reasons being pacemaker incompatibility or haemodynamic instability. 10 participants with a median age of 76.5 years, Charlson Comorbidity Index of 5.5, GBS 9 and RS 4 were included. Six participants had a negative BDC. Four had a positive BDC; one non-bleeding duodenal ulcer, one oozing Roux-en-Y anastomotic ulcer and two normal examinations. The 90-day mortality was 0% and there were no adverse events among the participants.Conclusion Introduction of a BDC as a triage tool may reduce the need for inpatient gastroscopies, otherwise indicated by high GBS/RS. We propose patients with suspected non-variceal AUGIB and a negative BDC can be safely managed as outpatients, irrespective of GBS/RS. Larger cohort data is needed to assess the long-term benefit, cost-effectiveness and complication rates.