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A male infant, born to parents in a non-consanguineous marriage presented with a 1-month history of itchy, fluid-filled lesions in a string-of-pearl appearance all over the body following administration of the first dose of pentavalent vaccination. The results of the immunological tests confirmed the diagnosis of bullous pemphigoid. He was treated with topical and oral corticosteroids along with oral dapsone, followed by good improvement. The child received subsequent doses of the vaccine without any further relapses.