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Background Cardiovascular diseases are the leading cause of mortality among women, yet their participation in cardiac rehabilitation (CR) programs remains lower than men’s. Strategies such as women-only CR groups and in-hospital liaison referrals may improve enrollment, but their impact on CR completion and cardiovascular events remains unclear.Aim This study evaluated the associations of (1) women-only vs. mixed-gender CR groups and (2) in-hospital liaison referrals vs. standard hospital referrals on women’s CR completion and cardiovascular event recurrence.Methods This is a retrospective longitudinal study conducted using records of adult women referred to the CR program at Hôtel-Dieu de Lévis (Canada) from May 2022 to February 2025. The 12-week program included supervised exercise, risk factor management, and education. We excluded non-hospital referrals and women who participated in a virtual, hybrid, or home-based program. Completion was defined as attending ≥70% of sessions. Recurrence of cardiovascular events was assessed using emergency visits and hospital admissions. We conducted multivariable logistic regressions adjusted for potential confounders.Results 118 women were included (mean age 69.4±9.2 years; 66.4% post-MI; median follow-up: 651 days). Women-only CR groups were associated with higher completion (OR=5.36, 95%CI[1.58, 18.22], p=0.007) and participation (+12.66%, 95%CI[3.23, 22.10], p=0.01) ( figure 1). In-hospital liaison referrals were also associated with higher completion (OR=3.70, 95%CI[1.00, 13.66], p=0.049). Women receiving both interventions had higher completion (OR=15.95, 95%CI[1.93, 131.66], p=0.01) and participation (+20.40%, 95%CI[7.32, 33.48], p=0.003) compared to women in mixed-gender groups with standard hospital referral. Although not statistically significant, women-only CR groups showed lower incidence of all-cause hospitalization (HR=0.51, 95%CI[0.15 to 1.73], p=0.3). Referral strategies were not associated with cardiovascular event recurrence.Abstract P08 Figure 1Comparision of completion rates according to A) the selected CR groups and B) the referral methodsConclusion These findings support the integration of structured women-only CR groups and in-hospital liaison referrals to improve program adherence.