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Background and Aims Pain management in clavicle surgery is challenging due to its complex innervation. The interscalene brachial plexus block has been traditionally used but carries risks such as phrenic nerve paralysis. The combined clavipectoral fascia (CPB) and superficial cervical plexus block (SCPB) has emerged as an alternative technique that may provide effective analgesia without impairing respiratory function. This study evaluates the efficacy and safety of CPB-SCPB in midshaft clavicle surgery. Ultrasound images of CPB and SCPB are attached.Methods A case series study was conducted in seven patients (six men, one woman, mean age 48.6 ± 15.6 years) undergoing surgery with CPB-SCPB. Pain levels were assessed using the VAS scale in the immediate postoperative period and at 24 hours, as well as the need for rescue analgesia and conversion to general anesthesia.Results VAS score 0 was observed in 85.7% of patients immediately postoperatively, and at 24 hours, all had VAS < 4. Only one patient required rescue analgesia (metamizole at 18 hours). No opioids were used. Two patients (28.6%) required conversion to general anesthesia. One minor complication (transient paresthesia in the neck and cheek) was recorded. Two patients were discharged as outpatient.Conclusions CPB-SCPB provides effective analgesia in clavicle surgery, reducing opioid use and facilitating early discharge. Its safety profile suggests it is a viable alternative to the interscalene block. Controlled studies are needed to confirm these findings.