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Thinking like a pathologist: anatomy-anchored artificial intelligence for liver pathology

jclinpath · 2025-12-31 · canonical JSON source

5 visible annotations · policy: published · automated confidence ≥ 75.00%

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In this issue of the Journal of Clinical Pathology, Dylan Windell and colleagues present a machine-learning model for evaluating liver inflammation in patients with metabolic-dysfunction-associated steatohepatitis (MASH) and autoimmune hepatitis (AIH).1 Unlike many recent pathology artificial intelligence (AI) systems that lean on weakly or self-supervised paradigms popular in tumour biology, this is a fully (indeed, deeply) supervised model designed to think like a pathologist.2