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Introduction The Bath Centre for Fatigue Services (BCFS) is a national Consultant Allied Health Professional-lead service, providing evidence-based treatments for a range of long-term health conditions predominantly ME/CFS, where longstanding fatigue impacts on daytime function and engagement in meaningful occupations.Presentations of fatigue vary and can be complex and multifactorial, involving multi-morbidities, anxiety, mental health conditions and neurodiversity. It can be challenging to understand where and how sleep features in the midst of such presentations. ME/CFS is a condition that is often considered as an explanation. However, is there enough awareness of CRSWDs to ensure individuals receive appropriate support and treatment?Method This case report presents a general practitioner (GP) referral to BCFS for a young autistic adult with suspected ME/CFS and the subsequent steps to identify an underlying sleep-related cause for their symptoms, drawing on current diagnostic criteria and published guidelines.Results The patient’s demographic and clinical/sleep history is shown in table 1. Sleep diary data demonstrated a non-24hr sleep/wake rhythm/disorder (N24SWD), with a step-wise delaying sleep phase (table 1). Delayed sleep-onset is present when trying to maintain a consistent bedtime. Sleep duration averages 8.6 hours over four weeks.Discussion The prevalence of N24SWD in the sighted population is uncommon (Malkani etal 2018). Carmassi etal (2019) suggest the prevalence may be higher in individuals with ASC due to reduced melatonin production and the role that melatonin is thought to play in circadian rhythm maintenance.There may be overlap between ME/CFS and CRSWDs (Jackson & Bruck 2012). Education in sleep medicine may help accurately identify causes of disrupted circadian rhythm, providing opportunity for appropriate diagnosis. Collaborative working across fatigue and sleep services, could optimise skills and resources to improve individual’s ability to engage in meaningful occupations and positively influence quality of life.Abstract O15 Table 1Patient demographic and clinical/sleep history