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Annotated abstract

Oesophageal sebaceous heterotopia with ducts mimicking epidermoid metaplasia: a rare diagnostic pitfall

jclinpath · 2025-12-15 · canonical JSON source

2 visible annotations · policy: published · automated confidence ≥ 75.00%

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Sebaceous heterotopia is a rare finding in the oesophagus with a prevalence of 0.05%.1 It is thought to represent a metaplastic process and is benign requiring no special clinical follow-up.2 3 Histologically, oesophageal sebaceous heterotopia (ESH) is characterised by lobules of sebaceous glands in the lamina propria, which lack an associated hair follicle. The glands may have associated excretory ducts and demonstrate a connection to the luminal surface through a channel lined by keratinising squamous epithelium with a granular cell layer resembling the epithelium of the follicular infundibulum in the skin.