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Background The COBATEST Network brings together community-based testing services across Europe, enabling the systematic collection of harmonised and disaggregated data on HIV, viral hepatitis, and sexually transmitted infections. Comprehensive, comparable, and multidimensional data are essential for understanding epidemiological patterns, identifying disparities across key populations, and monitoring the performance of community-based testing services. The recent updates to the COBATEST data collection system—through the EU-funded projects BOOST and CORE—primarily aim to strengthen the network’s capacity to capture high quality, standardised information across gender identities, age groups, and overlapping key population categories.Material and Methods This analysis includes all 2024 testing visits reported through the COBATEST online data collection tool. Standardised indicators were analysed across HIV, HCV, HBV, and syphilis testing, with results disaggregated by gender, age, and key population. Additional variables on drug use patterns and social vulnerabilities were also examined. Integrated testing practices and intersectionalities between key population were analysed using Venn diagrams.Results In 2024, 22,994 testing visits were registered from 73 CBVCT services in 10 European countries. The availability of harmonised, disaggregated data enabled comparisons across demographic and behavioural dimensions. Men who have sex with men, migrants, and people who use drugs were the most frequently tested groups, with notable overlaps between key population categories ( figure 1). Reactivity patterns varied substantially across gender identities and population subgroups, being transgender women and people who inject drugs those consistently showing the highest positivity rates across infections (table 1). Integrated testing was widely implemented, with nearly 20% of visits including rapid tests for all four infections (figure 1). Newly introduced variables on drug use provided granular insight into consumption routes, frequency, material sharing, opioid agonist treatment, and homelessness—critical factors for understanding vulnerability and guiding harm reduction strategies.Conclusions The 2024 COBATEST dataset demonstrates the value of collecting harmonised, disaggregated information to support evidence-based decision-making in community-based testing. Such data illuminate disparities across populations, uncover intersectional vulnerabilities, and enable cross-country comparability—ultimately strengthening prevention, early diagnosis, and linkage-to-care strategies. Expanding the adoption of standardised tools across to diverse community-based testing services, including harm-reduction services, and further improving completeness of disaggregated data will be key to advancing equitable and integrated infectious disease responses in Europe.Abstract OC5 Table 1HIV, HCV, HBV, and syphilis testing disaggregated by gender, age, and key populationAbstract OC5 Figure 1Combination of tests performed per testing visit and intersectionalities of key population groups (MSM, SW, PWUD, Migrants) among testing visits