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Annotated abstract

Endoscopic gastroenterostomy for malignant gastric outlet obstruction: the need for reintervention is variable

gutjnl · 2025-12-19 · canonical JSON source

6 visible annotations · policy: published · automated confidence ≥ 75.00%

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We read with great interest the study by Bang et al, comparing endoscopic ultrasound-guided gastroenterostomy (EUS-GE) with surgical gastrojejunostomy (SGJ) for malignant gastric outlet obstruction (GOO).1 They found that EUS-GE significantly reduced reinterventions for recurrent obstruction, consistent with earlier reports.2 However, another recent randomised controlled trial (RCT) and a meta-analysis of retrospective studies indicate similar reintervention rates for EUS-GE and SGJ.3 4 To clarify these discrepancies, we performed a pooled analysis of the two available RCTs and explored reasons for the differing outcomes (see PROSPERO CRD420251176835 and online supplemental table S1/figure S1). Statistical analyses were performed using R (V.4.2.1). Study characteristics are shown in online supplemental table 2.SP110.1136/gutjnl-2025-337514.supp1Supplementary data