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Introduction Post-partum angiopathy can manifest as posterior reversible encephalopathy syndrome (PRES), reversible cerebral vasoconstriction syndrome (RCVS), or eclampsia/pre-eclampsia. Our case series illustrates the diverse spectrum of neurological presentations, radiology, and outcomes.Case 1 A 30-year old woman, 2 weeks post-partum, developed recurrent episodes of left hemiparesis and dysarthria, with complete resolution in between. Blood pressure was 159/99 mmHg. MRI revealed diffusion restriction in the splenium and bilateral corona radiata. Anti-hypertensive medication was started. Symptoms continued for 8 days, prior to complete recovery.Case 2 A 33-year old woman, developed a sudden onset headache and tonic-clonic seizure, during caesarean section. She was given intravenous magnesium. MRI head showed bi-frontal convexity sub-arachnoid haemorrhage. Vascular imaging was normal. Recurrent thunderclap headaches continued for 8 weeks.Case 3 A 33-year old woman, 3 weeks post-partum, developed headaches and confusion. Blood pressure was 220 mmHg, and MRI head revealed diffuse cerebral oedema. Intravenous anti-hypertensive medication was started. GCS declined to 4, prompting intubation and transfer to a tertiary centre. Repeat neuro-imaging showed increased cerebral oedema; an intracranial pressure monitor was inserted. Despite maximal medical management for elevated intracranial pressure, she suddenly deteriorated with uncal herniation not amenable to surgery, and died.Conclusion Post-partum angiopathy is a serious condition, requiring prompt diagnosis, and aggressive blood pressure management, appropriate for the puerperal physiology. Whilst majority of patients have favourable outcomes, there are reports of fulminant and fatal cases, highlighting a role for surgical decompression in severe cases.