Through thick and thin: balancing venous thromboembolism prophylaxis initiation with intracranial hemorrhage progression after traumatic brain injury

Patients with traumatic brain injuries (TBIs) pose competing and potentially catastrophic risks of intracranial hemorrhage (ICH) progression and venous thromboembolic events (VTE).1 Knowing that the delay of chemoprophylaxis initiation (CP) >72 hours significantly elevates VTE risk among subpopulations of TBI patients,2 delineation of the optimal timing for CP is essential.