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79 Papilledema – don’t forget the sarcoid!

jnnp · 2025-11-26 · canonical JSON source

4 visible annotations · policy: published · automated confidence ≥ 75.00%

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Sarcoidosis is a chronic granulomatous disorder of unknown aetiology that can affect any organ, commonly the lungs, and is characterised by the presence of non-caseating granulomas. Neurosarcoidosis can affect the nervous system in 10% of cases and ocular involvement can range from 25% - 60%. We present the case of a 37 year old female who presented with incidental severe bilateral papilledema and a left lower motor nerve seventh palsy. The rest of her examination was unremarkable. CT, CT venogram and MRI head showed no abnormality. CT TAP revealed left hilar lymphadenopathy and endoscopic bronchial ultrasound (EBUS) with histology revealed non caseation granulomas cinching the diagnosis of sarcoidosis. CSF was also supportive showing lymphocytic pleocytosis. After extensive workup she was treated as neurosarcoid with ocular involvement with high dose steroids and had complete resolution of her facial nerve palsy and improvement in her optic disc swelling bilaterally. Our case highlights sarcoidosis as an unusual but treatable cause for papilledema.justine.edwards1@nhs.net