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Real-world validation of a prognostic clinical index to predict steroid response in acute severe colitis: a single tertiary centre retrospective study

gutjnl · 2025-12-05 · canonical JSON source

6 visible annotations · policy: published · automated confidence ≥ 75.00%

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We read with great interest the article by Adams et al in *Gut* on the development and validation of the Admission Model for Intensification of Therapy in Acute Severe Colitis (ADMIT-ASC) score to predict steroid response in acute severe ulcerative colitis (ASC). This index, which combines C reactive protein (CRP), albumin level and the UC Endoscopic Index of Severity (UCEIS), represents a significant advancement in ASC management. As early identification of steroid non-responders remains a clinical challenge, we aimed to validate the ADMIT-ASC score in a Belgian cohort and assess its predictive performance in routine tertiary care.