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While the lower oesophageal sphincter and oesophageal body have well defined normal ranges for manometric investigations in paediatrics, there is very limited data on the upper oesophageal sphincter (UOS) available for children, with most previous reports requiring significant additional manipulation of data outside of the commercially available software used to capture the data. 1 2 A retrospective review of oesophageal manometries carried out in a tertiary paediatric centre was carried out, with 30 patients randomly selected for additional upper oesophageal sphincter measurements to be extracted. Measurements of the upper oesophageal sphincter available within the Solar GI oesophageal manometry module (Laborie/MMS) were extracted, along with the baseline diagnosis following manometry. Achalasia has previously been shown to affect the upper oesophageal sphincter3 so two patients in the random sample who were diagnosed with achalasia were excluded from the analysis.28 patients were therefore included in the dataset, mean age 10.6±3.7 years, 11:17 M:F. The diagnostic outcomes of these patients were normal (12), rumination (4), ineffective peristalsis (8), belching (2) and reflux (2). The mean (±standard deviation) resting UOS pressure for 5 ml swallows of rehydration salt solution was 44.8 ± 22.2 mmHg with mean residual pressure of 1.1 ± 5.5 mmHg. Mean IRP 0.2s was -0.7 ± 5.3 mmHg and mean IRP 0.8s was 10.6 ± 6.7 mmHg.Ongoing work is underway to correlate manometric data with video fluoroscopy and other conditions as well as expand the sample to include all oesophageal manometries completed in the last 5 years to ensure access to a robust normal dataset for investigating children who present with symptoms of upper oesophageal sphincter dysfunction.References Damrongmanee A, El-Chammas K, Fei L, Zang H, Santucci N, Kaul A. Pharyngeal and upper esophageal sphincter motor dynamics during swallow in children. Neurogastroenterology & Motility 2021;33:e13962. https://doi.org/10.1111/nmo.13962Caruso AM, Bommarito D, Girgenti V, et al. Evaluation of dysphagia and inhalation risk in neurologically impaired children using esophageal high-resolution manometry with swallowing analysis. Children (Basel) 2022;9(12):1987. Published 2022 Dec 17. doi:10.3390/children9121987Huang CZ, Huang ZW, Liang HM, Wang ZJ, Guo TT, Chen YP. Upper esophageal sphincter abnormalities on high-resolution esophageal manometry and treatment response of type II achalasia. World J Clin Cases. 2020;8(4):723–735. doi:10.12998/wjcc.v8.i4.723