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Association between self-reported poor sleep status and ovulation rate in Chinese women with fertility intentions: a multicentre prospective cohort study protocol

bmjopen · 2026-05-15 · canonical JSON source

2 visible annotations · policy: published · automated confidence ≥ 75.00%

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Introduction In China, women of childbearing age, who constitute a major demographic of online consumers and professionals in emerging industries are increasingly experiencing significant sleep disturbances. Existing studies have predominantly focused on the association between sleep disorders and polycystic ovary syndrome, often overlooking the independent impact of sleep patterns on ovulatory function in the general population of women attempting conception. Specifically, the synergistic effect of blue light exposure from electronic devices and delayed sleep onset remains underexplored, and evidence regarding the relationship between sleep duration, sleep quality and ovulation rates is insufficient. The primary objective of this study is to investigate the association between sleep habits and ovulation rates among Chinese women with fertility intentions. Second, it aims to determine the correlation between these sleep habits and factors such as screen time, night shift work and regional differences. Third, using a user-friendly sleep monitoring wristband, the study seeks to clarify the quantitative relationship between objective sleep parameters (eg, sleep onset time, sleep efficiency) and ovulation rates in this population.Methods and analysis This is a 1.5-year multicentre prospective cohort study. Participants will be recruited from at least five reproductive medicine centres in mainland China between May 2025 and December 2026. The study will enrol women aged 20–50 years with fertility intentions. Baseline demographic information and habitual sleep patterns will be assessed through standardised questionnaires, with participants self-reporting their sleep conditions. Prepregnancy biochemical indicators and anthropometric data will be recorded. The primary outcome will be the ovulation rate, with secondary outcomes including pregnancy rate and miscarriage rate.Ethics and dissemination This research project has been approved by the Clinical Research Ethics Committee of Guangdong Provincial Maternal and Child Health Hospital (Approval No.20250072), and has also received approval from the Primary and Specialty Nursing Committee for implementation and development. All participants will be informed verbally and in writing about the study procedures and objectives prior to signing the consent form. Data confidentiality will be ensured, and participants may withdraw their consent at any stage of the research. The findings will be presented at international conferences and published in peer-reviewed scientific journals.