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Objectives To present the impact of caregiver-directed interventions on child development in rural areas of Guatemala.Methods Group sessions were conducted with mothers of children under two years in four communities, with a total of 95 participants, including breastfeeding and pregnant mothers. Sessions followed a participatory and culturally responsive approach, using native language and visual materials, and included both theoretical and practical components. Each session lasted three hours. Pre- and post-training questionnaires were applied to assess caregivers’ knowledge. Topics covered included nutrition and early childhood development.Results From 2022 to 2024, 111 mothers began training and 95 graduated; some did not complete due to various factors. Results showed increased knowledge among caregivers and notable changes in child-rearing practices. Most households adopted the recommendations provided, improving support for their children’s development.Conclusions Caregiver-directed interventions in Indigenous communities must be participatory, contextualized, and culturally responsive, with emphasis on the use of native language to ensure comprehension. Group sessions became spaces for learning and community building, strengthening support networks among caregivers.