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Cancer is an escalating global health crisis, and Africa remains deeply vulnerable.1 Research finds that the majority of new cancer cases worldwide occur in low-income countries, mostly in the African region, due to poverty, lack of awareness, prevention strategies, lifestyle change and industrialisation.1 2 While current global public health strategy involves promoting physical activity (PA) as a medicine,3 there is a discourse recognising exercise as a supplementary means of prevention and management of oncological conditions. According to the WHO, “all adults should undertake 150–300 min of moderate-intensity, or 75–150 min of vigorous-intensity physical activity, or some equivalent combination of moderate-intensity and vigorous-intensity aerobic physical activity, per week among children and adolescents, an average of 60 min/day of moderate-to-vigorous intensity aerobic physical activity across the week provides health benefits with regular muscle-strengthening activity for all age groups”.4 Evidence from Africa, although limited, supports the beneficial role of PA in cancer outcomes. A retrospective cohort study conducted in South Africa reported that individuals with stage I cancers who engaged in low levels of PA had a 16% lower risk of cancer progression or death, while those with moderate to high PA showed a 27% reduction. Such data remain scarce for most African populations beyond South Africa; these findings suggest that the magnitude of PA’s protective effect is both clinically meaningful and broadly consistent across cancer types, highlighting the urgent need for region-specific research to confirm and adapt PA prescriptions in African cancer care guidelines.1 4 Structured PA programmes show considerable contribution to risk mitigation and disease management (including cancer survival). While other regions are taking measures to integrate PA into patient care5 6 (when considering the patient’s physical condition, surgical intervention, treatment received, cardiac and other metabolic risk), PA remains absent from cancer control policies, treatment protocols and public health communications in many Sub-Saharan African countries.1 PA would be an appropriate strategy priority for low- and middle-income countries (LMICs) where growing cancer-related morbidity and mortality are observed.7