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Background and Aims Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare autoimmune disease which affects the sensory nerves, leading to weakness and sensory symptoms. Few studies have been reported on anesthetic management of this condition, thus our aim is to suggest an appropriate anesthetic plan for the management of a patient with CIDP, undergoing total hip arthroplasty.Methods A 63-year-old patient with CIPD required a total left hip arthroplasty due to osteonecrosis. A combined plan of general anesthesia and a femoral nerve block were decided on, due to concerns of high post-op pain levels and symptom aggravation. An ultrasound-guided nerve block was performed using 20 ml of 0,2% ropivacaine after GA was induced and the patient was intubated.Results The patient reported no pain post-op (VAS score 0). Adequate analgesia was achieved thereafter, and no worsening of sensory symptoms during the rehabilitation period was reported.Conclusions Due to successful patient outcome, a combination of GA and peripheral nerve blocks may be a suitable option for patients with CIPD and may be considered as an anesthetic plan for patients with this condition.