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This article is the first in a series on neurodevelopmental follow-up of infants born preterm or those born at term but admitted to neonatal intensive care. The discussions in this series also apply to infants and children with developmental or early acquired brain injuries or those with congenital disorders, such as congenital cardiac disorders, that increase their risk of neurodevelopmental problems. The focus is exclusively on central nervous system pathologies; peripheral nervous system and neuromuscular disorders are excluded.