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Annotated abstract

Beyond hypertension: quantifying the full risk landscape for heart failure in women

heartjnl · 2026-01-27 · canonical JSON source

3 visible annotations · policy: published · automated confidence ≥ 75.00%

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Heart failure (HF) is a leading cause of premature death and disability worldwide, and its burden among women presents unique challenges. Although the lifetime risk of HF is comparable in women and men, women are twice as likely as men to experience HF with preserved ejection fraction (HFpEF). HF in women often presents with atypical symptoms and remains underdiagnosed and undertreated.1 Yet despite these disparities, risk prevention strategies remain largely modelled on male-centric cohorts, prioritising traditional cardiometabolic risk factors while neglecting broader reproductive, psychosocial and environmental determinants of HF. This gap in practice and policy was recently flagged in the joint British Cardiovascular Societies’ (BCS) consensus statement with a call for a more holistic approach to take account of risk factors specifically related to female biology, alongside the traditional risk factors.2