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Successful ultrasound-guided epidural anaesthesia following failed spinal anaesthesia in a patient with neurofibromatosis 1

bmjcr · 2025-07-21 · canonical JSON source

4 visible annotations · policy: published · automated confidence ≥ 75.00%

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Neurofibromatosis type 1 (NF1) is a genetic disorder characterised by neurofibromas and skeletal anomalies, including lumbar kyphoscoliosis and dysmorphic sacral vertebrae. We report a rare case of a male in his late 30s with NF1 presenting with a left-sided hip dislocation and an unusual response to spinal anaesthesia. Spinal anaesthesia was attempted using 3 mL of 0.5% hyperbaric bupivacaine (dextrose 8%), resulting in a unilateral block. Pulmonary function tests did not favour general anaesthesia; hence, an MRI was performed that showed extensive abnormalities in the spine. The next day, ultrasound-guided epidural anaesthesia at T10–T11 was performed successfully with placement of an epidural catheter in situ for postoperative pain control. This is a rare phenomenon underlining the complexity of anaesthetic management in patients with NF1 and significant spinal abnormalities.