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Take-home message: This Chinese expert consensus focuses on the hematoporphyrin derivative (HpD) photodynamic therapy (PDT) in cervical high-grade squamous intraepithelial lesion (HSIL). It aims to provide systematic guidance for gynaecologists, oncologists, nursing professionals and PDT practitioners at all levels in the clinical application of HpD-PDT for the treatment of cervical HSIL.