Clinical outcomes of peritoneal dialysis in Southeast Asia: a scoping review protocol with a focused North American comparator

Introduction Peritoneal dialysis (PD) is delivered across diverse health-system contexts. In Southeast Asia (SEA), PD has been promoted to expand kidney replacement therapy access where haemodialysis capacity, geography and resources constrain care. This protocol describes a scoping review focused on reported PD clinical outcomes in SEA, with North America used only as a prespecified external comparator rather than as a control group, global benchmark or proxy for best practice.Methods and analysis This scoping review will follow Joanna Briggs Institute guidance and will be reported using Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). PRISMA Protocols (PRISMA-P) items are addressed where applicable. The review will be conducted from 1 May 2026 to 31 October 2026. Searches will identify sources published from 1 January 2000 to the planned final search date of 31 July 2026. MEDLINE, Embase, CENTRAL, Global Index Medicus, Google Scholar, citation searching and selected registry, professional, governmental and conference sources will be searched. No language restriction will be applied at the search stage. Eligible evidence will include peer-reviewed studies, registry or professional reports, governmental or institutional reports and conference abstracts or posters with extractable PD outcome data. Non-English sources will be screened using machine translation and extracted using targeted translation of relevant sections when feasible. Outcomes of interest include patient survival, technique survival and transition to haemodialysis, peritonitis and other infectious complications, hospitalisation and health service utilisation, cardiovascular outcomes, catheter-related complications and patient-reported outcomes when reported as clinical endpoints. Findings will be summarised descriptively and mapped by outcome domain and by region, with contextual factors noted when reported.Ethics and dissemination Ethics approval is not required because this review will synthesise published literature only. Findings will be disseminated through peer-reviewed publication and conference presentations, and the extracted dataset and search strategies will be shared in supplementary materials or an online repository, subject to journal policy.Trial registration This protocol is registered on the Open Science Framework (OSF): https://osf.io/3dkvx/.