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A 41-year-old male presented to the Emergency Department following an abrupt onset of altered behaviour and word finding difficulty. A CT head demonstrated a left frontal lobe haemorrhage, angiographic imaging was normal. MRI Brain revealed the presence of multiple microhaemorrhages detected on SWI, typical of Cerebral Amyloid Angiopathy (CAA). Amyloid PET scan was positive, adding weight to the hypothesis that, despite his young age, the underlying cause for his stroke was CAA.The initial CT head demonstrated evidence of a previous craniotomy, something neither the patient nor his partner could account for. Following review of his records we were able to establish that the patient had sustained a head injury aged 8, that had ultimately required a craniotomy for dural repair due to persisting CSF leak. The operation note indicated that lypophilised dura had been used to repair this leak.We hypothesise that this case represents a presentation of iatrogenic CAA. In recent years there has been increasing recognition and reporting of patients presenting with amyloid angiopathy at a younger age. Many of these patients have a history of neurosurgical intervention, typically decades prior to presentation.Shika.Habershon@rlbuht.nhs.uk